On Guard: Science Meets Daily Immune Support
The Story Behind On Guard
For years, we’ve known from experience that doTERRA’s On Guard blend supports wellness. Many of us have our own stories—whether it’s diffusing during seasonal challenges or using it as daily protection. That’s experiential evidence.
But now science is confirming what experience has always told us. Beyond Petri dishes and test tubes, clinical testing in humans shows how On Guard works inside the body.
The Study: What Happens When You Take On Guard?
Researchers designed a simple but groundbreaking test:
Baseline blood sample was taken.
One dose of On Guard tablet (3 tablets) was consumed.
Blood samples were collected at 3 and 5 hours later.
They focused on two areas:
Results
White Blood Cells – The Sentries Wake Up
Within hours, researchers saw a gentle increase in white blood cells, especially lymphocytes.
Lymphocytes produce antibodies, seek out invaders, and destroy marked cells.
This wasn’t a panic spike—it was a healthy response. It looked like soldiers standing at attention, awake and ready for orders.
Cytokines – Balanced Communication
Two key signaling molecules increased:
Interleukin-10 (IL-10): Anti-inflammatory, helping calm and balance the immune system.
Interleukin-13 (IL-13): A regulator, like a fire chief directing the action.
Interleukin-2 receptors increased—these receptors determine the pace and amount of immune response.
Analogy: Imagine a call center adding more phone lines so it can handle a bigger influx of calls.
The body was preparing and organizing itself, not wasting resources.
The Big TAKEAWAY: Preparation, Not Panic
So when taken together, these results suggest our cells are in a poised preparatory state. They’re ready and waiting.
The immune system isn’t forced into burning its resources. Instead, it’s like storing food in advance of a famine or stacking sandbags before a flood. That way, when a quick, coordinated effort is needed, everything is already in place.
The Big Takeaway: 👉 On Guard helps the body prepare before threats arrive.
Practical Application: How to Use On Guard Products
1. On Guard Protective Blend (Oil)
Use: Diffuse in your home, or dilute and apply to feet.
How Often: 1–2 times daily for steady support.
2. On Guard Softgels
Use: Take 1–2 with meals.
How Often: Daily for maintenance during seasonal threats, or up to 3–4/day during times of high exposure.
3. On Guard Chewable Tablets (used in the study)
4. On Guard Household Products
Use: Sanitizing spray & wipes for surfaces, oral care, and hand hygiene.
How Often: As part of your daily routine.
OIL GROUP DISCUSSION QUESTIONS:
Personal Experience – Have you ever used On Guard (or another essential oil) during a seasonal challenge? What did you notice?
Science Meets Experience – How does it strengthen your confidence when research confirms what you’ve already experienced?
Immune System Analogy – The study describes white blood cells as “soldiers at attention.” How does that picture help you understand what’s happening in your body?
Preparation vs. Panic – Why is it important that the immune system prepares without overreacting? Can you think of a life example where preparation made the difference?
Everyday Application – After learning this, how might you use On Guard differently or more intentionally in your daily routine?